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Makarand Anaspure (Marathi: मकरंद अनासपुरे) is an Indian actor. He is popular on television and has acted in several Marathi movies. He is mainly known for his comedy and intelligent roles in Marathi cinema. He has also played a cameo for one episode in the Hindi serial Tu Tu Main Main and as an Umpire along with co-stars - Bharat Jadhav (Pachadlela fame) and Arun Kadam (Pran Jaaye Par Shaan Na Jaaye). He credits Nana Patekar for his access into the film industry. Makarand started his career using his unique proficiency in the Marathwada accent of Marathi language, and it is one of his specialties. Makarand came to fame after having worked in Saatchya Aat Gharat and Kaydyacha Bola.

Makarand Anaspure entered into direction by directing the Marathi film Dambis in 2011. He has produced a couple of movies.

In September 2015, Nana Patekar and Makarand Anaspure established an organisation called Naam Foundation, which works to provide aid to farmers overcome by drought conditions in Maharashtra, India